Since Google released Chrome last year, I've gotten used to regularly using two browsers on my PC: Google Chrome for all of my "simple" personal browsing such as webmail, and Firefox for more advanced browsing such as website development. This also tends to create a nice separation of personal (Chrome) versus work (Firefox) tasks.
However, one thing that has bothered me for some time is the (slightly) proprietary nature of Google Chrome... don't get me wrong, Chrome is built from the opensource Chromium project, so it's not all that proprietary, but still, something does not quite sit right with me.